In 1967, Ernesto ?Che? Guevara resigns from his Cuban government posts to secretly make his latest attempt to spread the revolution in Bolivia. However, Che must face grim realities about few troops and supplies, his failing health and a local population who largely does not share his idealistic aspirations. As the US supported Bolivian army prepares to defeat him, Che and his beleaguered force struggle against the increasingly hopeless odds.